Mechanism-based Inactivation of Cytochrome P450 3a (cyp3a) by Hiv Protease Inhibitors
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چکیده
256 words Introduction 473 words Discussion – 1238 words d) List of non-standard abbreviations: CYP, cytochrome P450; b5, cytochrome b5; AUC, area under the plasma concentration time curve; ki, reversible inhibition constant; kdeg, rate constant for enzyme degradation; kinact, the maximal rate constant for inactivation; KI, inactivator This article has not been copyedited and formatted. The final version may differ from this version. JPET Fast Forward. Published on November 2, 2004 as DOI: 10.1124/jpet.104.075416 at A PE T Jornals on O cber 9, 2017 jpet.asjournals.org D ow nladed from
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